Pharma Deals Review, Vol 2024, No 3 (2024)

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Gilead Collaborates with Merus For Novel Antibody-Based Trispecific T-Cell Engagers

Lalit Mishra

Abstract


In order to strengthen its oncology portfolio, Gilead Sciences has entered into a research collaboration, option and license agreement with Merus to discover novel dual tumour-associated antigens (TAA)-targeting trispecific antibodies. The collaboration, that could be worth up to US$1.58 B, will leverage Merus’ proprietary Triclonics® platform along with Gilead’s oncology expertise to develop preclinical research programmes. This deal could represent a significant stride towards innovative therapies and underscores the immense potential of TAA-targeting trispecific antibodies to advance the treatment of cancer.

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