Pharma Deals Review, Vol 2018, No 10 (2018)

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Roche Expands Cell Therapy Collaboration with SQZ Biotech

Michelle Liu

Abstract


Showing its confidence in SQZ’s intracellular delivery platform, Roche has expanded its research collaboration with the company and paid US$125 M in upfront and near-term payments to co-develop and co-commercialise antigen presenting cell therapies for the treatment of oncology indications. The agreement builds on the 2015 collaboration between the two companies focused on delivering tumour-associated antigens into B cells extracted from patients using SQZ’s technology in a deal worth US$500 M in upfront and potential clinical, regulatory and sales milestone-based payments.

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