Pharma Deals Review, Vol 2019, No 1 (2019)

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Codiak Biosciences’ Exosome Therapeutics Attracts Jazz Pharmaceuticals

Michelle Liu

Abstract


Investing in its cancer and haematological portfolio, Jazz Pharmaceuticals has partnered up with Codiak Biosciences to develop exosome therapeutics in a deal worth US$1.1 B. Using Codiak’s engEx™ precision engineering platform, the companies will develop five therapies targeting oncogenes that are undruggable with current modalities, including neuroblastoma -RAS and signal transducer and activator of transcription 3. Preclinical data showed that selective delivery of a therapeutic resulted in significantly improved potency and reduced toxicity.

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