Pharma Deals Review, Vol 2012, No 9 (2012)

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SFJ Pharmaceuticals to Conduct Phase III Trial of Pfizer’s Dacomitinib in First-Line Advanced NSCLC

Heather Cartwright

Abstract


SFJ Pharmaceuticals has formed its second collaborative development agreement with Pfizer, this time to conduct a Phase III trial to evaluate Pfizer’s pan-Her (pan-human epidermal growth factor receptor) inhibitor dacomitinib (PF-00299804) as a first-line therapy for patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC) with activating EGFR (epidermal growth factor receptor) mutations. The NSCLC market continues to move towards molecular-targeted therapies used alongside companion diagnostics to guide treatment decisions.



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