Pharma Deals Review, Vol 2015, No 6 (2015)

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Juno Therapeutics and Editas Medicine Collaborate to Develop Next-Generation CAR-T Therapeutics Using CRISPR/Cas9

Heather Cartwright & Keshav Mahawar

Abstract


Signalling its intent to stay at the head of the cellular immunotherapy field, Juno Therapeutics has agreed to collaborate with genome editing specialist Editas Medicine to create next-generation chimeric antigen receptor (CAR-T) and high-affinity T cell receptor (TCR) therapies for the treatment of cancer. With the deal, Juno will leverage Editas’ CRISPR (clustered, regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) technology with the aim of expanding its pipeline into solid tumours.



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