Pharma Deals Review, Vol 2023, No 2 (2023)

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Amgen Signs US$2 B Licensing Agreement with Synaffix for Next-Generation ADCs

Lalit Mishra & Lucy Haggerty

Abstract


Demonstrating its continued interest in antibody-drug conjugate (ADC) therapeutics, Amgen has agreed to pay up to US$2 B for exclusive access to Synaffix's ADC technology. The deal, which is currently for one undisclosed therapeutic, involves technology platforms GlycoConnect™, HydraSpace™ and select toxSYN™ linker-payloads; Amgen also has the opportunity to develop an additional four therapeutics. The agreement marks Synaffix's twelfth out-licensing agreement as pharmaceutical firms demonstrate increasing interest in the potential of its ADC technology platforms for cancer treatments.

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